THE DIVERSITY OF SERUM ANTI-DSG3 IGG SUBCLASSES HAS A MAJOR IMPACT ON PEMPHIGUS ACTIVITY AND IS PREDICTIVE OF RELAPSES AFTER TREATMENT WITH RITUXIMAB

The Diversity of Serum Anti-DSG3 IgG Subclasses Has a Major Impact on Pemphigus Activity and Is Predictive of Relapses After Treatment With Rituximab

IntroductionWe studied the distribution and in vitro pathogenicity of anti-DSG3 IgG subclasses during the course of pemphigus vulgaris (PV).MethodsWe longitudinally studied the distribution of anti-DSG3 IgG subclasses (before versus after treatment) in sera from PV patients, using an addressable-laser bead immunoassay (ALBIA).The in vitro pathogeni

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Improving the Assessment of Mild Cognitive Impairment in Advanced Age With a Novel Multi-Feature Automated Speech and Language Analysis of Verbal Fluency

tg02-0325m Introduction: Clinically relevant information can go uncaptured in the conventional scoring of a verbal fluency test.We hypothesize that characterizing the temporal aspects of the response through a set of time related measures will be useful in distinguishing those with MCI from cognitively intact controls.Methods: Audio recordings of a

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An Update on the Complexity and Importance of Accurately Diagnosing Post-Traumatic Stress Disorder and Comorbid Traumatic Brain Injury

As awareness for diagnosing and screening patients for trauma has grown, more effective evidence-based treatments are available to treat post-traumatic stress disorder (PTSD).Despite these gains, several patients are non-responsive to care and research has shifted to determining barriers for cure or improvement.With the advent of modern warfare, th

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